| Title | Possible interactions with drugs of herbals used for weight loss enhancement | |
| Authors | Michael Chourdakis, Sofia Kellidou, Georgios Papazisis, Chrysanthi Sardeli, Anastasia Argyriou and Dimitrios Kouvelas
Department of Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Greece |
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| Citation | Chourdakis, M., Kellidou, S., Papazisis, G., Sardeli, C. et al.: Possible interactions with drugs of herbals used for weight loss enhancement, Epitheorese Klin. Farmakol. Farmakokinet. 24(2): 128-129 (2010) | |
| Publication Date | 2010 | |
| Full Text Language | English | |
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
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| Keywords | Herbals, weight loss, adverse effects, drug interactions. | |
| Other Terms | Review article | |
| Summary | The use of dietary supplements, including herbals, vitamins and minerals, is extensive. The majority of patients have little or no information about the possible risks and adverse effects from interactions with prescribed medicines. Concerns about herbal medications include their actual pharmacological properties. Among the more common herbs used for weight loss are Ephedra sinica (ephedra), Hoodia gordonii (hoodia), Citrus aurantium (bitter orange) and Larrea tridentate (chaparral), and are mostly used in an effort to enhance metabolism. Receiving ephedra with various medications may lead to interactions, (i.e. dysrythmias, hypertension, anxiety). Hoodia has been found to suppress appetite, however it has a potential hepatoxicity and therefore safety and efficacy have to be validated. Bitter orange acts similarly to ephedra and when received together with MAOIs can lead to tachycardia and hypertension. Chaparral acts similarly to caffeine and also has a mild diuretic effect. Its use may be complicated with renal, hepatic and neurological toxicity, and is also considered carcinogenic. Patients should be extremely cautious when receiving herbal medicines especially when are on any prescribed medication. | |
| References | 1. National Center for Complementary and Alternative Medicine: Ephedra. Herbs at a Glance 2006. http://nccam.nih.gov/health/ephedra/ataglance.htm
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| Relative Papers |
Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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