| Title | Association study of the single nucleotide polymorphism (SNP), rs6983267, at region 3 of chromosome 8q24, with prostate cancer in the Greek population | ||
| Authors | Amalia Papanikolopoulou1, Olfert Landt2, Martin Reczko3 and Nikolaos Drakoulis1
1. Dept of Pharmaceutical Technology, School of Pharmacy, University of Athens, Greece 2. TIB MOLBIOL, Berlin, Germany 3. Biomedical Sciences Research Center, Alexander Fleming, Vari, Greece |
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| Citation | Papanikolopoulou, A., Landt, O., Reczko, M., Drakoulis, N.: Association study of the single nucleotide polymorphism (SNP), rs6983267, at region 3 of chromosome 8q24, with prostate cancer in the Greek population, Epitheorese Klin. Farmakol. Farmakokinet. 24(2): 187-189 (2010) | ||
| Publication Date | 2010 | ||
| Full Text Language | English | ||
| Order – Buy | Ηλεκτρονική Μορφή: pdf (10 €) – Digital Type: pdf (10 €)
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| Keywords | Genetic variants, prostate cancer, chr8q24 and SNPs, prevalence of rs6983267. | ||
| Other Terms | Review article | ||
| Summary | Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting an association study at the Greek population to investigate the frequency and the susceptibility of one SNP, rs6983267, located at the region 3 of chromosome 8q24, to the prostate cancer, we found highly significant correlation (Odds ratio=2.83 and p-value=0.002). Comparing the findings to other studies, conducted in northern Europeans, the population attributable risk (PAR%) and the frequency of the at risk allele (G vs T) were higher at the Greek population with an independent risk for the carriers to develop the disease. | ||
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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