Τόμος 20 (2006) – Τεύχος 2 – Άρθρο 24 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 24 (2006) – Issue 2 – Article 24 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Department of Experimental Pharmacology, Medical School, University of Athens, Athens, Greece

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the effects of cadmium (Cd) on food and water consumption, as well as on body weight (BW) of adult rats, following subchronic oral administration, and b) the potential protective role of zinc (Zn), calcium (Ca) and L-cysteine (Cys) on the above parameters, in Cd co-administration. Several losses were recorded throughout the experiment, mainly in the Cd- and the Ca⁺Cd^–treated groups. Our data revealed that Cd subchronic oral administration, provoked a significant decrease of rat BW and food consumption that were adequately reversed by Zn and Cys. Moreover, a significant reduction of Cd^–intake rate was observed throughout the experiment, but no differences between the Cd-treated groups were observed as concerns water (and thus Cd) consumption.

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