Τόμος 22 (2008) – Τεύχος 2 – Άρθρο 52 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 22 (2008) – Issue 2 – Article 52 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title A pharmacoeconomic comparison study of an lc/ms method used for the bioequivalence study of donepezil compared with a similar HPLC method for the same substance
Authors K. Katsikaris, A. Papaioannou, A. Gotsi and N. Karagiannidis

Bioequivalence Mentor S.A.

Citation Katsikaris, K., Skopelitis, I., Papaionannou, A., Gotsi, A., Karagiannidis, N.: A pharmacoeconomic comparison study of an lc/ms method used for the bioequivalence study of donepezil compared with a similar HPLC method for the same substance, Epitheorese Klin. Farmakol. Farmakokinet. 22(2): 193-194 (2008)
Publication Date 23-25 May 2008
Full Text Language English
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Keywords Donepezil, bioequivalence study, LC/MC, HPLC.
Other Terms Review article
Summary The presented study depicts the differences in cost of a bioequivalence study conducted on an LC/MS system when compared to a similar method using an HPLC system. The comparison of the two methods is based on data concerning the overall cost for each method. This includes consumables, reagents, instrument maintenance, as well as demands regarding personnel and equipment.
References 1. Yasui-Furulori N., Furuya R., Takahata T., Tateishi T.: Determination of donepezil, an acetycholinesterase inhibitor, in human plasma by high-performance liquid chromatography with ultraviolet absorbance detection. J. Chromatography B 768: 261-265 (2002)

2. Lu Y.H., Wen H.M., Li W., Chi Y.M., Zhang Z.X.: Determination of donepezil in human plasma by HPLC-MS. Yao Xue Bao 38: 203-206 (2003)

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ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 2008 – ANNUAL SUBSCRIPTION 2008
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