| Title | Evaluation of the bioequivalence of two pravastatin products in tablets (40 mg/tab) in healthy volunteers | |
| Authors | Eleftheria Karatza¹, Chrisovaladou Tsoukia¹, Stamatia Pagoni³, Mary Kounoukla¹, Spiros Kouris¹, Maria Katsiampani¹, Dimitra Charisi¹, Nikolaos Karagiannides¹ and Michael Koupparis²
1. Mentor Laboratories S.A., Spaton Avenue 197, Pallini, Attiki, Greece 2. Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens 3. General National Hospital of Athens G. Gennimatas, 3rd Internal Medicine Dept., Athens, Greece |
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| Citation | Karatza, E., Tsoukia, Ch., Pagoni, S., Kounoukla, M., Kouris, S. et al: Evaluation of the bioequivalence of two pravastatin products in tablets (40 mg/tab) in healthy volunteers, Epitheorese Klin. Farmakol. Farmakokinet. 20(2): 201-203 (2006) | |
| Publication Date | Accepted for publication: 19-20 May 2006 | |
| Full Text Language | English | |
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| Keywords | Pravastatin determination, atilipemic agent, hydroxy-pravastatin. | |
| Other Terms | review article | |
| Summary | An efficient liquid chromatographic method with ultraviolet detection, using clobazam as internal standard is described for the determination of antilipemic agent Pravastatin in healthy volunteers. The two preparations of Pravastatin could be considered bioequivalent, regarding the ranges of values of the pharmacokinetic parameters for Pravastatin and its active metabolite Hydroxy-Pravastatin. | |
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Online ISSN 1011-6575
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