Title | Pregabalin combined with epidural analgesia in chronic cancer pain patients | ||
Authors | C. Pourzitaki1, H. Logotheti2, C. Sardeli1, G. Papazisis1, P. Arampatzis2 and D. Kouvelas1
1. Department of Pharmacology, School of Medicine, Aristotle University, Thessaloniki, Greece 2. Department of Anesthesiology, Achillopouleion General Hospital, Volos, Greece |
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Citation | Pouritzaki, C., Logotheti, H., Sardeli, C., Papazisis, G., Arampatzis, P. et al.: Pregabalin combined with epidural analgesia in chronic cancer pain patients, Epitheorese Klin. Farmakol. Farmakokinet. 22(2): 308-309 (2008) | ||
Publication Date | 23-25 May 2008 | ||
Full Text Language | English | ||
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Keywords | Cancer pain, analgesia, pregabalin, quality of life. | ||
Other Terms | Review article | ||
Summary | Patients with chronic cancer pain are challenging to manage and evidence-based clinical recommendations for pharmaceutical treatment are needed. In order to investigate the role of pregabalin in treating patients suffering from cancer pain a prospective study of combining epidural analgesia with pregabalin was conducted. The changes in the Visual Analogue Scale (VAS) of the above patient’s pain were estimated. According to our results pregabalin administration improves the VAS score affecting also their quality of life. | ||
References | 1. Galluzzi K.E.: Managing neuropathic pain. J. Am. Osteopath Assoc. 107(10 Suppl 6): ES39-48 (2007)
2. Guindon J., Walczak J.S., Beaulieu P. (2007). Recent advances in the pharmacological management of pain. Drugs 67: 2121-2133 (2007 3. Johannessen Landmark C.: Antiepileptic drugs in non epilepsy disorders: relations between mechanisms of action and clinical efficacy. CNS Drugs 22: 27-47 (2008) 4. Vanotti A., Osio M., Mailland E., Nascimbene C., Capiluppi E., Mariani C.: Overview on pathophysiology and newer approaches to treatment of peripheral neuropathies. CNS Drugs 21(Suppl 1): 3-12; 45-46 (2007) 5. Eisenberg E., River Y., Shifrin A., Krivoy N.: Antiepileptic drugs in the treatment of neuropathic pain. Drugs 67: 1265-1289 (2007) 6. The EuroQol Group: EuroQol – a new facility for the measurement of health-related quality of life. Health Policy 16:199-208 (1990); Biomech. 26(Suppl. 1): 23-40 (1993) |
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Online ISSN 1011-6575
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Articles published in this Journal are Indexed or Abstracted in: • Chemical Abstracts • Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE SCImago Journal and Country Rank Factor
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