Τόμος 18 (2004) – Τεύχος 1 – Άρθρο 42 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Διεθνής Έκδοση – Volume 18 (2004) – Issue 1 – Article 42 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-International Edition

Title Ultrastructural alterations following 4-NQO administration, in rats, after experimental oral cavity cancer
Author L. Economou1, A. Sioga1, K. Antoniades2, H. Tsoukali3 and A. Manthos1

1Department of Histology-Embryology. Medical School, 2Department of Oral and Maxillofacial Surgery, Dentistry School, 3Department of Toxicology, Aristotle University, Thessaloniki, Greece

Citation Economou, L., Sioga, A., Antoniades, K., Tsoukali, H. and Manthos, A.: Ultrastructural alterations following 4-NQO administration, in rats, after experimental oral cavity cancer, Epitheorese Klin. Farmakol. Farmakokinet. 18(1): 102-104 (2004)
Publication Date Accepted for publication: 2004
Full Text Language English
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Keywords Ultrastructural alteration, 4-NQO, Oral Cavity Cancer, tongue, Neoplasmatic lesions
Other Terms review article
Summary
References 1.         Chadially F.N.: Diagnostic Electron Microscopy of Tumors. Butterworth Heinemann, London, 1980

2.         Boyd N.M., Read P.C.: Factors associated with the development of neoplasia. J. Oral Pathol. Med, 17: 202-207 (1988)

3.         Kenneth D„ Me Chatchey, Zardo Ft.: The Jaws and Orai Cavity in Diagnostic Surgical Pathology. 2nd ed, Vol 1 ed. Sternberg S.S, Raven Press, Ltd, New York, 1994

4.         Reibel J.: Tobacco and oral diseases. Update on the evidence, with recommendations. Med. Princ. Pract. 125 pi: 22-23 (20030

5.         Wallenius K., Lekholm U.: Oral cancer in rats induced by the water soluble carcinogen 4-nitroquinoline-1-oxide. Odontol. Rev. 24: 39-48 (1973)

6.         Wong P., Wilson D.: 4-Nitroquinoline 1-oxide-induced carcinogenesis in the rat palate. J. Oral Pathol. 12.375-384

(1983)

7.         Nauta J.M., Roodenberg J., Nikkels P., Witjes M., Ver- mey A.: Epithelial dysplasia and squamous cell carcinoma of the Wistar rat mucosa: 4-NQO model. Head and Neck: 441-449 (1996)

8.         Dayan D., Hirshberg A., Kaplan I., Rotem N., Bodner L.: Experimental tongue cancer in desalivated rats. Oral Oncol. 33·. 105-109 (1997)

9.         Steidler N.E., Reade P.C.: Experimental induction of oral squamous cell carcinomas in mice with 4-nitroquinoline-1-oxide. Oral Surg. Oral Med. Oral Pathol. 57: 524-531

(1984)

10.       Jiang D.J., Nilson D.F., Niebkin O.N.: Ultrastructural features of normal epithelium and 4-Nitroquinoline-1-oxide induced carcinomas of the rat tongue. J. Comp. Path. 109: 375-381 (1993)

11.       Kandarkar S.V., Sawant S.S, Readw P.C.: Ultrastructural changes to the palatal mucosa following the application of 4-Nitroquinoline 1-oxide(4NQO) and vitamin C. Oral Oncol. 34: 247-252 (1998)

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