Review of Clinical Pharmacology and Pharmacokinetics – International Edition Volume 38 (2024) – Supplementary Issue 2

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Antibacterial activity of the alcoholic extract of berberine against Staphylococcus aureus isolated from burn and wound infections

Ola Abbas Khdhair1,*A green circle with white letters Description automatically generated, Yazi Abdullah Jassim2A green circle with white letters Description automatically generated, Noor Abed Alreda Alkremy1A green circle with white letters Description automatically generated,Taif Hussein Al-Ameedy1A green circle with white letters Description automatically generated
1Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Hillah, Iraq
2Department of Biology, College of Science, University of Babylon, Hillah, Iraq

*Corresponding author: Ola Abbas Khdhair, Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Hillah, Iraq; Tel.: +964-(0)7827225952
E-mail: pharm.ola.abbas@uobabylon.edu.iq

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Published: 5 May 2024; https://doi.org/10.61873/FMPT5825

Abstract
Burns and wounds destroy the physical skin which is the body’s natural barrier to the external environment. As a result the burned area is prone to infection and colonization by microorganisms. The most common pathogenic colonizing bacterium is Staphylococcus aureus. In order to solve the problem of bacterial resistance to antibiotics, some medicinal plants have been used so as to determine their effectiveness against S. aureus. Among these plants, we have herein used the alcoholic extract of berberine. Our results suggest that the alcoholic extract of berberine, at a concentration 250 mg/mL, can exert a high inhibitory efficacy against S. aureus.

Keywords: Staphylococcus aureus, burns, wounds, berberine, infection

Please cite as:
Khdhair O. A., Jassim Y. A., Alkremy N. A. A., Al-Ameedy T. H. Antibacterial activity of the alcoholic extract of berberine against Staphylococcus aureus isolated from burn and wound infections. Rev. Clin. Pharmacol. Pharmacokinet. Int. Ed. 38 (Sup2): 137-139 (2024). https://doi.org/10.61873/FMPT5825

 

 

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