Τόμος 4 (1986) – Τεύχος 2 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 4 (1986) – Issue 2 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Ε. AGGELAKAS AND G. GOUMENOS

4: 8-14 (1986)

PHARMAKON-Press: Epitheorese Klin. Farmakol. Farmakokinet.

4: 8-14 (1986)

The improvement of some pathological situations that followed the admi­nistration of placebo was studied by a number of investigators during the past years. Extensi­ve studies of “phenomenon-placebo” showed a multifactorial mechanism of action whose clini­cal characteristics are mainly associated with the personalities of patient and physician and their relationship during the treatment. Under these conditions the “placebo” acts as a real drug having action, adverse effects and intera­ctions with other drugs. The ethical aspect of “placebo-therapy” initiated considerable debate among scientists.

1. Shapiro, A.K., Morris, L.A.: The placebo effect in medi­cal and psychological therapies. In: Handbook of Psy­chotherapy and Behavior Change. An empirical analy­sis (S.L. Gorfield, A.C. Bergin, eds), p. 369, John Wiley and Sons, New York, 1979
2. Dorland’s Medical Dictionary. Twenty-Third Edition, W.B. Saunders Company
3. Leslie, Α.: Ethics and practice of placebo therapy. Am. J. Med. 16: 854 ( 1954)
4. Ford, P.L., ed.: The Wirting of Thomas Jefferson. Vol. IX, p. 78, Putnam, New York 1898
5. Wolff, N.G., Dubois, E.F., Gold, H.: Cornell conferences on therapy: Use of placebos in therapy. Ν.Y. St. J. Med. 46: 1718 (1946)