Τόμος 33 (2015) – Τεύχος 1 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 33 (2015) – Issue 1 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Συσχέτιση Λιπιδίων Ορού σε Ασθενείς με Οξεία Λεμφοβλαστική Λευχαιμία

Εμμανουέλα-Νίκη Σουρά¹, Αρετή Σεβαστού¹, Βασιλική Βυλλιώτου², Γεώργιος-Αλβέρτος Καρίκας¹

¹Τμήμα Ιατρικών Εργαστηρίων, Σχολή Επαγγελμάτων Υγείας και Πρόνοιας, Τεχνολογικό
Εκπαιδευτικό Ίδρυμα Αθηνών, Αθήνα, Ελλάς. ²Βιοχημικό Εργαστήριο, Ε.Α.Ν. Πειραιά, Μεταξά, Πειραιάς, Ελλάς

Emmanouela-Niki Soura¹, Areti Sevastou¹,Vasiliki Villiotou², George-Albert Karikas¹

¹Department of Medical Laboratories, Faculty of Health and Caring Professions, Technological
Educational Institute of Athens, Egaleo, Athens, Hellas ²Laboratory of Biochemistry, Cancer Hospital of
Piraeus, Metaxa, Piraeus, Hellas

2. Watson James D., Caudy Amy A., Mayers Richard M., Witkowski Jan A.: Ανασυνδυασμένο DNA. 1η Εκ., Ι. Μπάσδρα και ΣΙΑ Ο.Ε., Αθήνα, ISBN: 978-960-88412-5-3, (2007)

3. Παπαϊωάννου Μ.: Μελέτη της ελάχιστης υπολειμματικής νόσου στην οξεία β-λεμφοβλαστική λευχαιμία ενηλίκων και παιδιών με μοριακές τεχνικές. Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ), 2002

4. Ιωαννίδου-Παπακωνσταντίνου A.: Αιματολογία Ι. 1η Εκ., Βήτα, Αθήνα , ISBN: 978-960-8071-57-5, (2003)

5. Stevens Al., Lowe J.: Ιστολογία του ανθρώπου. 3η Εκ., Πασχαλίδης, Αθήνα, ISBN: 987-960-399-652-1 (2008)

6. Πάγκαλης Γ.: Αιματολογία στην Κλινική Πράξη. 1η Εκ., Πασχαλίδης, Αθήνα, ISBN: 978-960-399-776-4, (2008)

7. Bassan R., Hoelzer D.: Modern therapy of acute lymphoblastic leukemia. J. Clin. Oncol. 29(5): 532-543 (2011)

8. Hoffbrand A.V., Moss P.A.H., Pettit J.E. (Eds): Αιματολογία. 5η Εκ., Παρισιάνου, Αθήνα, ISBN: 978-960-394-579-6 (2009)
9. Keene Ν. (Ed.): Childhood leukemia: a guide for families, friends & caregivers. 4th ed., CA: O’Reilly, Sebastopol, ISBN: 978-1-4493-8043-4, (2002)

10. Pui Ching-Hon.: Childhood Leukemias. 3rd Edn, Cambridge University Press, UK, ISBN: 987-0-521-19661-1 (2012)

11. Panagiotou J.P., Poluchronopoulou-Androulakaki S.: Leukemogenesis in childhood. Etiologic factors and pathogenetic mechanisms. Arch. Hellen. Med. 17(6): 576-583 (2000)

12. Berg J.M., Tymoczko J., Stryer L. (Eds): Biochemistry. 5th edition, Volume 2, W.H. Freeman, New York, 2002

13. Conde-Knape K., Bensadoun A., Sobel J.H., Cohn J.S., Shachter N.S.: Overexpression of apoC-I in apoE-null mice severe hypertriglyceridemia due to inhibition of hepatic lipase. J. Lipid Res. 43(12): 2136-2145 (2002)

14. Chung B.H., Dashti N.: Lipolytic remnants of human VLDL produced in vitro: effect of HDL levels in the lipolysis mixtures on the apoCs to apoE ratio and metabolic properties of VLDL core remnants. J. Lipid Res. 41(2): 285-297 (2000)

15. Kwan B.C., Kronenberg F., Beddhu S., Cheung A.K.: Lipoprotein metabolism and lipid management in chronic kidney disease. J. Am. Soc. Nephrol. 18(4): 1246-1261
(2007)

16. Brautbar A., Virani S.S., Belmont J., Nambi V., Jones P.H., Ballantyne C.M.: LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia. J. Lipid Res. 53(3): 556-560 (2012)

17. Packard C.J., Demant T., Stewart J.P., Bedford D., Caslake M.J., Schwertfeger G., Bedynek A., Shepherd J., Seidel D.: Apolipoprotein B metabolism and the distribution
of VLDL and LDL subfractions. J. Lipid Res. 41(2): 305-318 (2000)

18. Morton R.E., Greene D.J.: CETP and lipid transfer inhibitor protein are uniquely affected by the negative charge density of the lipid and protein domains of LDL. J.
Lipid Res. 44(12): 2287-2296 (2003)

19. Vance D., Vance J. (Eds): Biochemistry of Lipids Lipoproteins, and Membranes. 5th ed., Elsevier B.V., USA, ISBN: 978-0-444-53219-0, 2008

20. Gotto A.M., Assmann G., Carmena R.: The ILIB Lipid Handbook for Clinical Practice: Blood Lipids and Coronary Heart Disease. 2nd Ed., International Lipid Information Bureau, New York, 2000

21. Kemik O., Sumer A., Kemik A.S., Hasirci I., Purisa S., Dulger A.C., Demiriz B., Tuzun S.: The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. World J. Surg. Oncol. 8: 85 (2010)

22. Scott N.J., Cameron V.A., Raudsepp S., Lewis L.K., Simpson E.R., Richards A.M., Ellmers L.J.: Generation and characterization of a mouse model of the metabolic
syndrome: apolipoprotein E and aromatase double knockout mice. Am. J. Physiol. Endocrinol. Metab. Mar 302(5): E576-584 (2012)

23. Khovidhunkit W., Kim M.S., Memon R.A., Shigenaga J.K., Moser A.H., Feingold K.R., Grunfeld C.: Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host. J. Lipid Res. 45(7): 1169-1196 (2004)

24. Khovidhunkit W., Memon R.A., Feingold K.R., Grunfeld C.: Infection and inflammation-induced proatherogenic changes of lipoproteins. J. Infect. Dis. 181(Suppl 3): S462-472 (2000)

25. Popa C., Netea M.G., van Riel P.L., van der Meer J.W., Stalenhoef A.F.: The role of TNF-a in chronic inflamematory conditions, intermediary metabolism, and cardiovascular risk. J. Lipid Res. 48(4): 751-762 (2007)

26. Ranjit S., Boutet E., Gandhi P., Prot M, Tamori Y., Chawla A., Greenberg A.S., Puri V., Czech M.P.: Regulation of fat specific protein 27 by isoproterenol and TNF-
α to control lipolysis in murine adipocytes. J. Lipid Res. 52(2): 221-236 (2011)

27. Memon R.A., Bass N.M., Moser A.H., Fuller J., Appel R., Grunfeld C., Feingold K.R.: Down-regulation of liver and heart specific fatty acid binding proteins by endotoxin and cytokines in vivo. Biochim. Biophys. Acta. 1440(1): 118-126
(2000)

28. Brown N.F., Mullur R.S., Subramanian I., Esser V., Bennett M.J., Saudubray J.M.: Feigenbaum A.S., Kobari J.A., Macleod P.M., McGarry J.D., Cohen J.C.: Molecular
characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme. J. Lipid Res. 42(7): 1134-1142 (2001)

29. Westerterp M., Berbée J.F., Delsing D.J., Jong M.C., Gijbels M.J., Dahlmans V.E., Offerman E.H., Romijn J.A., Havekes L.M., Rensen P.C.: Apolipoprotein C-I bindsfree fatty acids and reduces their intracellular esterification. J. Lipid Res. 48(6): 1353-1361 (2007)

30. Gierens H., Nauck M., Roth M., Schinker R, Schürmann C., Scharnagl H., Neuhaus G., Wieland H., März W.: Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements. Arterioscler.
Thromb. Vasc. Biol. 20: 1777-1783 (2000)

31. Anuurad E., Rubin J., Chiem A., Tracy R.P., Pearson T.A., Berglund L.: High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans. J. Clin. Endocrinol.
Metab. 93: 1482-1488 (2008)

32. Borggreve S.E., De Vries R., Dullaart R.P.: Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin:cholesterol acyltransferase
and lipid transfer proteins. Eur. J. Clin. Invest. 33(12): 1051-1069 (2003)

33. Tietge U.J., Maugeais C., Lund-Katz S., Grass D., deBeer F.C., Rader D.J.: Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol
and apoA-I in response to inflammation in human apoA-I transgenic mice. Arterioscler. Thromb. Vasc. Biol. 22: 1213-1218 (2002)

34. Stanley R.T., Laura J.T., Courtney C.R.: Peroxisomes, oxidative stress, and inflammation. World J. Biol. Chem. 3(5): 93-97 (2012)

35. Moschovi M., Trimis G., Apostolakou F., Papassotiriou I., Tzortzatou-Stathopoulou F.: Serum lipid alterations in acute lymphoblastic leukemia of childhood. J. Pediatr. Hematol. Oncol. 26(5): 289-293 (2004)

36. Mandal C., Mandal C., Chandra S., Schauer R., Mandal C.: Regulation of O-acetylation of sialic acids by sialate-Oacetyltransferase and sialate O-acetylesterase activities in childhood acute lymphoblastic leukemia. Glycobiology 22(1): 70-83 (2012)

37. Langdana A., Tully N., Molloy E., Bourke B., O’Meara A.: Intensive enteral nutrition support in pediatric bone marrow transplantation. Bone Marrow Transplant, 27(7): 741-746 (2001)

38. Hockenberry Μ.: Symptom management research in children with cancer. J. Pediatr. Oncol. Nurs. 21(3): 132-136 (2004)