Τόμος 18 (2000) – Τεύχος 1 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 18 (2000) – Issue 1 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

 

Τίτλος – Title

PPAR-Υποδοχείς και Αντιαθηρωσκληρωτικοί Μηχανισμοί

PPAR-Receptors and Αtherosclerotic Μechanisms

Συγγραφέας – Author

Βασίλης A. Κόκκας,  Κωνσταντίνος Λ. Παπαδόπουλος, Παύλος Κ. Παπαδόπουλος

Εργαστήριο Φαρμακολογίας και Β΄ Καρδιολογική Κλινική, Ιατρικό Τμήμα, Αριστοτέλειο Πανεπιστήμιο, Θεσσαλονίκη, Ελλάς

B.A. Kokkas, C.L. Papadopoulos, P.C. Papadopoulos

Departments of Pharmacology and 2nd Cardiol­ogy, Medical Scholl, Aristotle University, Thes­saloniki, Greece

Παραπομπή – Citation

Κόκκας,Β.Α., Παπαδόπουλος,Κ.Λ.,  Παπαδόπουλος,Π.Κ. : PPAR-Υποδοχείς και Αντιαθηρωσκληρωτικοί Μηχανισμοί, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 18 : 11-17 (2000)

Kokkas,B.A., Papadopoulos,C.L., Papadopoulos,P.C. : PPAR-Receptors and Αtherosclerotic Μechanisms, Epitheorese Klin. Farmakol. Farmakokinet. 18: 11-17 (2000)

Ημερομηνία Δημοσιευσης – Publication Date
25-11-1999 – 1999-11-25
Γλώσσα Πλήρους Κειμένου –
Full Text Language

Ελληνικά – Greek

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Λέξεις κλειδιά – Keywords

Υποδοχείς ενεργοποιούμενοι από πολλαπλασιαστή υπεροξεισωματίων, αντιαθηρωσκληρωτικοί μηχανισμοί

Peroxisome proliferator-activated receptors, atherosclerotic mechanisms
Λοιποί Όροι – Other Terms

Άρθρο

Article

Περίληψη – Summary

Η δυσλιπιδαιμία, οι διαταραχές στο μεταβολισμό της γλυκόζης και η φλεγμονή του αγγειακού τοιχώματος είναι βασικοί παράγοντες που αλληλοεμπλέκονται και προάγουν τους μηχανισμούς ανάπτυξης και εξέλιξης της αθηροσκλήρωσης. Οι υποδοχείς – PPAR ασκούν αποτρεπτικό ρόλο στους μηχανισμούς αυτούς και προστατεύουν το αγγειακό τοίχωμα.

Dislipidemia, glucose metabolism disorders and inflammation are crucial factors for the development of atherosclerosis. PPAR-re­ceptors play a major protective role by interfering with mechanisms related to the above factors.

Αναφορές – References
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