Τόμος 3 (1985) – Τεύχος 2 – Άρθρο 2 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 3 (1985) – Issue 2 – Article 2 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Α Review of the Cadmium Toxicology

GEORGE IKONOMIDIS

^{Τομέας Φαρμακευτικής Χημείας, Τμήμα Φαρμακευτικής, Πανεπιστήμιο Θεσσαλονίκης}

3: 23-34 (1985)

PHARMAKON-Press: Epitheorese Klin. Farmakol. Farmakokinet.

3: 23-34 (1985)

Cadmium, Toxicology

In this review, the toxicology of cadmium is presented. Thus, after a reference to the importance of the cadmium toxicity (this metal is one of the most toxic heavy metallic environmental pollutants) and after a brief pre­sentation of the chemistry of cadmium, the analytical toxicology of cadmium (biological and environmental samples) is introduced. The in­dustrial uses of cadmium, its potential toxicity, type, extent and frequencies of the cadmium poisoning such as professional, food, environ­mental, accidental, acute and chronic, have been presented in detail. The toxicokinetics (absorption, distribution, excretion) of cadmium, the mechanism of action on the body as well as on the organ, tissue, cellular and subcellu­lar level are discussed in detail. The symptoma­tology of the cadmium poisoning and the bo­dy’s natural defensive mechanisms are also shown. The serious and insidious nature of the cadmium poisoning is demonstrated; finally measures for reducing the incidence and ways of more effective treatment for this poisoning have been suggested.

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