Τόμος 3 (1985) – Τεύχος 2 – Άρθρο 3 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 3 (1985) – Issue 2 – Article 3 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Oral Diseases Induced by Drugs and Other Bioactive Agents

S. T. PLESSAS

^{Τμήμα Επιστημονικής Πληροφόρησης Φάρμακον-Τύπος}

3: 35-44 (1985)

PHARMAKON-Press: Epitheorese Klin. Farmakol. Farmakokinet.

3: 35-44 (1985)

 Oral Diseases

Drugs and other bioactive environ­mental agents may induce a wide spectrum of orofacial disease. The unwanted effects can present as direct local effects (soft and hard tissue damage, tooth discoloration), as systemic pharmacological effects (xerostomia, ptyalism, salivary gland pain, sialosis, taste disturban­ce, ecological imbalance), as secondary oral effects (immunosuppression, haemopoietic ef­fects, nutritional deficiency), as drug-induced immunological effects (contact hypersensitivity), or as indirect effects (erythema multiforme, lichenoid responses, benign mucous membrane pemphigoid, desquamative gingivitis, pemphi­gus, lupus erythematosus). Clinicians should be aware that a proportion of oral mucous mem­brane and hard tissue lesions can be caused by drugs. The early diagnosis and the successful management of drug-induced lesions of the oral cavity is of a primary importance. It is clear that dental and medical practitioners should obtain for every patient a full, current history including both prescribed and proprietary medi­cines.

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