Τόμος 6 (1988) – Τεύχος 1 – Άρθρο 5 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 6 (1988) – Issue 1 – Article 5 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

6: 54-59 (1988)

PHARMAKON-Press: Epitheorese Klin. Farmakol. Farmakokinet.

6: 54-59 (1988)

The literature regarding sexual dysfunction as a side effect(s) of antihypertensive drugs is limited tο nume­rous case reports; well-controlled studies of incidence rates are rare. The most common types of sexual disorders induced by antihypertensive medications include de­creased libido, impotence, impaired or retrograde ejaculatoin and gynaecomastia in males; and decreased libido, decreased vaginal lubrication, and inability to achieve orgasm in females. Side effects have been reported for thiazides and related diuretics, spironolactone, β-adrenergic blockers, me­thyldopa, clonidine, reserpine, prazosin, hydralazine; for recently available agents, minoxidil and captopril, their mechanisms of action suggest that they will not cause sexual problems, and evidence, or rather lack of it, supports the assumption tο date.

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