| Τίτλος – Title | Χρήση φαρμάκων κατά την Τρίτη Ηλικία
Drugs in the elderly |
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| Συγγραφέας – Author | Σταύρος Τ. Πλέσσας
Stavros T. Plessas |
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| Παραπομπή – Citation | Πλέσσας, Σ.Τ.: Χρήση φαρμάκων κατά την Τρίτη Ηλικία, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 2: 84-101 (1983)
Plessas, S.T.: Drugs in the elderly, Epitheorese Klin. Farmakol. Farmakokinet. 2: 84-101 (1983)
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| Ημερομηνία Δημοσιευσης – Publication Date | Ιούλιος – 1983 – July 1983 | |
| Γλώσσα Πλήρους Κειμένου – Full Text Language |
Ελληνικά – Greek | |
| Παραγγελία – Αγορά – Order – Buy |
Ηλεκτρονική Μορφή: pdf (15 €) – Digital Type: pdf (15 €) pharmakonpress[at]pharmakonpress[.]gr |
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| Λέξεις κλειδιά – Keywords | Υπερήλικες, ασθενείς, φάρμακα, νόσος, δοσολογία, ανταπόκριση, απορρόφηση
Elderly persons, patients, drugs, illness, dose, responsiveness, absorption |
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| Λοιποί Όροι – Other Terms | Άρθρο Article |
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| Περίληψη – Summary | The elderly persons (60 years of age and over) constitute an increasing proportion of patient population. As a group, elderly patients have more illness, take more drugs and they are particurarly susceptible to adverse drug reactions than younger patients. In elderly the responsiveness to drugs is altered because of changes in the pharmacokinetics and pharmacodynamics and of influence of accociated deseases. The rate or the amount of drug absorbed from the gastrointestinal tract are probably unaltered. The elderly differs from the young in the quantity of drug delivered to the target-site because of alteration in the processes of drug distribution and elimination. These processes are affected by the changes in body composition (decrease in lean body mass, total body water and serum albumin), in cardiac output, in liver and cerebral blood flow (diminished) and in glomerular and tubular function of the kindney (declined). The clinician should realize that many diseases from which the elderly patient suffers do not require drug treatment and must, also, take particular care of the added risks for these patients in the case that a drug therapy is decided. Only those drugs which the patient really needs should be prescribed. In general, the elderly patients require smaller doses of drugs than are given to the young adults. Drugs usually given in reduced doses include aminoglycosides, benzodiazepines, carbamazepine, chlormethiazole, digoxin, haloperidol, levodopa, metoclopramide, pethidine, thioridazine, thyroxine and vitamin D. Other drugs, as barbiturates, bethanidine, carbenoxoione, chrolpropamide, hlorthalidone, debrisoquine, guanethidine, nitrofurantoin, pentazocine and phenylbutazone should be avoided as possible. Dose regimens should be as simple aspossibie (special packaging, clear labelling) and drug therapy should be managed by a responsible neighbour or relative. | |
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| ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ 1983 – ANNUAL SUBSCRIPTION 1983 | |
| Γλώσσα Πλήρους Κειμένου – Full Text Language |
Ελληνικά – Greek |
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