Τίτλος – Title
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Θεραπευτική Αντιμετώπιση της Υπερπλασίας του Ενδομητρίου
Therapeutic Management of Endometrial Hyperplasia |
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Συγγραφέας – Author
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Γεώργιος Ιατράκης1,2, Στέφανος Ζερβούδης1,2, Αναστασία Μπόθου2,3, Κυριάκος Μητσάκος-Μπαρμπαγιάννης2, Σταύρος Φωτόπουλος2, Παναγιώτης Πεϊτσίδης2, Ειρήνη Τομαρά2,3, Παναγιώτης Τσικούρας4, Γεώργιος Γαλάζιος4 1Τμήμα Μαιευτικής, Σχολή Επαγγελμάτων Υγείας & Πρόνοιας (ΣΕΥΠ), Τεχνολογικό Εκπαιδευτικό Ίδρυμα (ΤΕΙ) Αθήνας, Αθήνα, 2ΡΕΑ Μαιευτική Γυναικολογική Κλινική, Αθήνα, 3Τμήμα Ιατρικής, ΠΜΣ Έρευνα στη Γυναικεία Αναπαραγωγή, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ), Αθήνα, 4Μαιευτική-Γυναικολογική Κλινική Πανεπιστημιακού Γενικού Νοσοκομείου Αλεξανδρούπολης, Ελλάς Georgios Iatrakis1,2, Stefanos Zervoudis1,2, Anastasia Bothou2,3, Kyriakos Mitsakos-Barbagiannis2, Stavros Fotopoulos2, Panagiotis Peitsidis2, Eirini Tomara2,3, Panagiotis Tsikouras4, Georgios Galazios4 1Department of Midwifery, Faculty of Health and Caring Professions, Technological Educational Institution (TEI) of Athens, Athens, 2Rea Maternity Hospital, Athens, 3Medical School, National and Kapodistrian University of Athens (NKUA), Athens, 4University General Hospital and University of Alexandroupolis, Alexandroupolis, Greece |
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Παραπομπή – Citation
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Ιατράκης,Γ., Ζερβούδης,Σ., Μπόθου,Α., Μητσάκος-Μπαρμπαγιάννης,Κ., Φωτόπουλος,Σ., Πεϊτσίδης,Π., Τομαρά,Ε., Τσικούρας,Π., Γαλάζιος,Γ. : Θεραπευτική Αντιμετώπιση της Υπερπλασίας του Ενδομητρίου, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 34: 91-97 (2016)
Iatrakis,G., Zervoudis,S., Bothou,A., Mitsakos-Barbagiannis,K., Fotopoulos,S., Peitsidis,P., Tomara,E., Tsikouras,P., Galazios,G. : Therapeutic Management of Endometrial Hyperplasia, Epitheorese Klin. Farmakol. Farmakokinet. 34: 91-97 (2016)
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Ημερομηνία Δημοσιευσης – Publication Date
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4 Νοεμβρίου 2016 – 2016-11-04
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Γλώσσα Πλήρους Κειμένου –
Full Text Language |
Ελληνικά – Greek |
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Λέξεις κλειδιά – Keywords
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Υπερπλασία ενδομητρίου, άτυπη υπερπλασία, διαγνωστική απόξεση, προγεσταγόνα, ενδομήτριο σπείραμα με προγεστερόνη
Εndometrial hyperplasia, atypical hyperplasia, diagnostic curettage (D&C), progestins, intrauterine device (IUD) with progestins
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Λοιποί Όροι – Other Terms
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Άρθρο Article |
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Περίληψη – Summary
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Οι συγγραφείς αναπτύσσουν το θέμα της υπερπλασίας του ενδομητρίου, τονίζοντας τις διαγνωστικές μεθόδους (ενδοκολπικό υπερηχογράφημα, Pipelle, απόξεση, υστεροσκόπηση). Η υπερπλασία διαχωρίζεται σε απλή, σύνθετη, με ή χωρίς ατυπία. Η αντιμετώπισή της ποικίλλει σε γυναίκες πριν και μετά την εμμηνόπαυση. Η θεραπεία βασίζεται στα προγεσταγόνα, στα LHRH ανάλογα και στο ενδομήτριο σπείραμα με προγεστερόνη.
The authors described the management of endometrial hyperplasia regarding diagnostic tools [vaginal ultrasound, Pipelle, curettage (D&C), hysteroscopy]. Endometrial hyperplasia could be simple, complex, with or without atypia. The treatment depends on the status: premenopause or postmenopause. The options are progestins, LHRH analogues and endometrium device with progesterone
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Αναφορές – References1
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1. Chu C.S.: Endometrial Hyperplasia and Uterine Cancer. In: Bader TJ (ed). Ob/Gyn Secrets. Philadelphia, Elsevier Mosby 2005.
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Obstet. 132(1): 34-38 (2016) 20. Hillard P.J.A.: Benign Diseases of the Female Reproductive Tract. In: Berek JS (ed). Berek & Novak’s Gynecology. Philadelphia, Lippincott Williams & Wilkins 2007. 21. Behnamfar F., Ghahiri A., Tavakoli M.: Levonorgestrel-releasing intrauterine system (Mirena) in compare to medroxyprogesterone acetate as a therapy for endometrial hyperplasia. J. Res. Med. Sci. 19(8): 686-690 (2014) 22. Gallos I.D., Devey J., Ganesan R., Gupta J.K.: Predictive ability of estrogen receptor (ER), progesterone receptor (PR), COX-2, Mlh1, and Bcl-2 expressions for regression and relapse of endometrial hyperplasia treated with LNG-IUS: a prospective cohort study. Gynecol. Oncol. 130(1): 58-63 (2013) 23. Ismail M.T., Fahmy D.M., Elshmaa N.S.: Efficacy of levonorgestrel-releasing intrauterine system versus oral progestins in treatment of simple endometrial hyperplasia without atypia. Reprod. Sci. 20(1): 45-50 (2013) 24. 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