Τόμος 2 (1984) – Τεύχος 2 – Άρθρο 4 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 2 (1984) – Issue 3 – Article 4 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Interferon: 27 Years after its Discovery

S.I. Coliais

^{Τμήμα Βιολογίας, Σχολή Θετικών Επιστημών, ΑΠΘ}

2: 149-160 (1984)

PHARMAKON-Press: Epitheorese Klin. Farmakol. Farmakokinet. 2: 149-160 (1984)

 Interferon

Ιnterferon was first described as an antiviral agent secreted in the culture medium after infection of cells with viruses. Today, 27 years later, several other properties of interferon are known: Interferon is conside­red a potent inhibitor of cell growth, a modu­lator of the immunological system and an anti­neoplastic agent. In this article are described: the recent progress on the characterization of interferon and the genes coding for it, the mechanisms of interferon synthesis . and its action and the methods for its mass production especially with the new technology of recombinant DNA. Some information is finally given on the clinical applications of interferon to hu­mans.

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