Open Access Research
Antibacterial, antioxidant and cytotoxic activities of Conyza Canadensis ethanolic extract
Basma KH. Alani1
, Shahad Basil Ismael2, Hadeel Mohamed Khalaf2, Ruqaya Mohammed Al-ezzy2,*
1Department of Plant Biotechnology, College of Biotechnology, Al- Nahrain University, Jadriya, Baghdad, Iraq
2Department of Molecular and Medical Biotechnology, College of Biotechnology, Al- Nahrain University, Jadriya, Baghdad, Iraq
*Corresponding author
Ruqaya Mohammed Al-ezzy, Department of Molecular and Medical Biotechnology, College of Biotechnology, Al- Nahrain University, Jadriya, Baghdad, Iraq. Tel.:07704236821; e-mail: Ruqaia.alezzy@nahrainuniv.edu.iq
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Published: 15 October ; https://doi.org/10.61873/QLNM1916
Abstract
Background: Medicinal herbs are widely valued for their therapeutic potential Conyza canadensis, with a long history of treating various ailments was the subject of this recent research. Aim: The study aimed to evaluate the total phenols and flavonoids, antioxidant, antibacterial and cytotoxicity activity of Conyza canadensisethanolic extract in vitro. Methodology: The aerial parts of the plant were extracted with 70% ethanol. The extract was analyzed for total phenolic and flavonoid content, antioxidant capacity using DPPH assay, antimicrobial effects against selected pathogens, and cytotoxicity on HepG2 cells using the MTT assay. Results: The extract showed high phenolic (226.28 ± 12.67 mg/g GAE) and flavonoid content (123.1 ± 16.25 μg/mL). The DPPH assay indicated dose-dependent scavenging activity, surpassing that of vitamin C. Antibacterial activity was moderate to strong, with inhibition zones ranging from 13 mm to 31 mm depending on concentration and organism. The MTT assay revealed significant cytotoxicity against HepG2 cells at higher doses. Conclusion: Conyza canadensis exhibits promising antioxidant, antibacterial, and cytotoxic properties attributed to its phytochemical content.
Keywords: extract, herb, health, antioxidant, cell line
Please cite as:
Alani B. K. H., Ismael S. B., Khalaf H. M., Al-ezzy R. M.: Antibacterial, antioxidant and cytotoxic activities of Conyza Canadensis ethanolic extract Epitheorese Klin. Farmakol. Farmakokinet. 43(Sup1): 21-24 (2025). DOI: 10.61873/QLNM1916
pISSN 1011-6575 • eISSN 2945-1914