Background: The occipital cortex is positioned on the back of the brain, and it is responsible for processing visual information. Ketamine is a drug used as an anesthetic. Common anesthetics can cause neurotoxicity, with the occipital cortex being one of the most vulnerable areas. Continue reading
Background: One effective second-generation triptan for migraine attacks is sumatriptan. Following oral use, it has a 40% restricted bioavailability because of the first-pass metabolism. Aim: To develop the best intranasal Solusomes formula as a substitute that delivers into the brain directly, improving its bioavailability, and removing the first-pass outcome was the aim of this effort. Continue reading
Background: Self-medication is one of the irrational drugs used; it is defined as using medicines to treat self-diagnosed diseases without consulting a healthcare professional. Nonsteroidal anti-inflammatory drugs (NSAIDs) are groups of analgesic medications that are used by millions of people around the world with or without prescription. Inappropriate self-medication can have several potential risks, such as harmful interactions with prescribed medicines and inappropriate duration of use. Continue reading
Children are more prone to develop gingivitis as a result of poor brushing and flossing proficiency, a lack of dedication to maintaining excellent oral hygiene, morphological variance in deciduous teeth, and a diet that encourages the growth of pathogenic oral bacteria. Aim: The aim of this study is to compare the therapeutic effect of a Salvia officinalis (Common Sage) extract mouth rinse related to that of Chlorhexidine mouth rinse, as well as the pediatric patient’s tolerance to their taste. Continue reading
Cryptococcus neoformans is a significant pathogenic yeast that causes severe infections in immunocompromised individuals, such as those with respiratory diseases, cancer, kidney failure, and meningitis. Early diagnosis and treatment are crucial in managing the infections. The study was conducted at Al-Batoul Hospital and Baqubah Teaching Hospital to isolate and diagnose Cryptococcus neoformans and assess potential antifungal treatments Continue reading
Medical statistics confirm that an increase in the likelihood of high blood pressure in individuals leads to a range of complications such as heart failure, stroke, or kidney failure, while a decrease can result in cell damage, particularly to the brain, due to inadequate oxygen and nutrient supply to tissues. Given this context, the research problem revolves around examining the impact of treatment and age on patients with varying blood pressure levels. Continue reading
Background: Amoebiasis, an intestinal infection caused by the parasitic amoeba Entamoeba histolytica, presents varying symptoms from none to severe. Traditional non-herbal treatments often carry adverse effects, prompting interest in herbal remedies. Aim: This study evaluates the effectiveness of Tamarindus indica (T. indica) and Cynodon dactylon (C. dactylon) extracts against E. histolytica. Continue reading
Co-crystallisation is a useful technique that can be used to improve important physicochemical properties of drugs that have solubility troubles, without any chemical modification. Aim: This study investigates the co-crystallization of the poorly soluble drug famotidine (FMT) with either nicotinamide (NIC) or urea as co-formers. Methodology: The method employed for preparation was solvent evaporation at a predetermined stoichiometric ratio. Continue reading
Plant extracts from Nigella sativa seeds were employed to synthesize silver nanoparticles (AgNPs) from silver nitrate solution. The AgNPs were characterized by spectroscopy, UV spectrophotometry, scanning electron microscopy (SEM), and F-TIR. Thirty female Albino Wistar rats were divided mainly into (3) groups (Group 1, Group 2: Group 2a and Group 2b) where (10) rats have been distributed for each. Continue reading
The anti-Müllerian hormone (AMH), secreted by granulosa cells in the preantral and the small antral ovarian follicles, is a predictor of the ovarian oocyte reserve. Aim: To investigate the correlation between low serum AMH levels (≤1.5 ng/mL), ovarian stimulation protocols, oocyte number, antral follicle count, age, and pregnancy outcomes in Iraqi women undergoing intracytoplasmic sperm injection (ICSI). Continue reading
