Τόμος 18 (2004) – Τεύχος 1 – Review of Clinical Pharmacology and Pharmacokinetics-Διεθνής Έκδοση – Volume 18 (2004) – Issue 1 – Review of Clinical Pharmacology and Pharmacokinetics-International Edition

1 Thrombin-induced angiogenesis: therapeutic implications
Michael E. Maragoudakis
2 Signaling pathways in the control of angiogenesis by nitric oxide
M. Ziche
3 Modulation of neuronal transmission and function by nitric oxide in the brain
Athineos Philippu, Helmut Prast, Ariane Hornick and Nicolas Singewald
4 Structural and functional interactions of NO-sensitive guanylyl cyclase
Doris Koesling, Evanthia Mergia, Michael Russwurm, Florian Mullershausen
5 Signaling through NO and cGMP-dependent protein kinase
Franz Hofmann, Jens Schlossmann and Robert Feil
6 Pharmacogenetics and pharmacogenomics: the road to individualized pharmacotherapy
U.A. Meyer
7 Mad about smads in pulmonary fibrosis and hypertension
Oliver Eickelberg
8 The glucocorticoid receptor in asthma and why it cannot cure the disease
Michael Roth
9 Clinical pharmacological principles in therapeutic drug monitoring (TDM)
Folke Sjoqvist
10 The practice of TDM: the dialogue between the clinical pharmacological laboratory and the prescriber
Milan Grundmann
11 On the mode of action of thrombin-mediated angiogenesis: functional characterization of RGD sequence within thrombin
Matthew Papakonstantinou, Nikos E. Tsopanoglou, Christodoulos Flordellis and Michael E. Maragoudakis
12 Reactive oxygen species are implicated in physiological angiogenesis in vivo and in vitro
C. Polytarchou and E. Papadimitriou
13 Perillyl alcohol attenuates in vitro angiogenesis, modulates angiogenic factor production and inhibits cell proliferation and survival in endothelial and tumour cells
H. Loutrari, V. Skouridou, F.N. Koiisis, C. Roussos and A. Papapetropoulos
14 Prothymosin α suppresses the TGF-β1-enhanced production of tissue inhibitor of metalloproteinases-1 but not of IL-6 in human synovial fibroblasts
G. Nezi, M. Giannakouli, S. Goura, E, Panagiotopoulos, A.P. Andonopoulos, E. Giannopoulou and A.J. Aletras
15 Structural and functional characterization of the dimerization sites of soluble guanylyl cyclase
Z. Zhou, Ch. Roussos and A. Papapetropoulos
16 The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat
Nikolaos Pitsikas, Antonello E. Rigamonti and Eugenio E. Muller
17 DNA/RNA methylation inhibitors block murine erythroleukemia cell differentiation and promote accumulation of discrete small RNA species: implications in activation of silent DNA sequences by pharmacological agents
Ioannis S. Vizirianakis, Sotirios S. Tezias and Asterios S. Tsiftsoglou
18 Production of prion protein (PrPc) in transfected murine erythroleukemia (MEL) and neuronal N2a cells overexpressing PrP RNA transcripts
Dimitrios Gougoumas, loannis S. Vizirianakis, Theodoros Sklaviadis and Asterios S. Tsiftsoglou
19 Application of the atomic force microscopy technique to the study of recombinant prion protein and its potential ligand interactions
G. Bloukas, K. Kotta, S. Kunze, S. Gnoth, J. Metze, W. Bodemer, C.H. Panagiotidis and T. Sklaviadis
20 Effects of cadmium on memory and brain antioxidant status of adult rats: protection by zinc, calcium and L-cysteine
G. Carageorgiou, V. Tzotzes, A. Zarros, A. Sideris and S. Tsakiris
21 SCEs and PRIs as indicators of structure-biological activity relationship of newly synthesized steroidal esters
D. Mourelatos, Z. Iakovidou, E. Mioglou, E. Karapidaki, A. Koutsourea, E. Arsenou, M. Fousteris and S. Nikolaropoulos
22 Neurosteroids and new synthetic analogs protect sympathoadrenal cells against apoptosis, regulating multiple prosurvival factors
G. Charalampopoulos, C. Tsatsanis, I. Alexaki, N. Avlonitis, E. Polakis, T. Calogeropoulou, E. Castanas, A.N. Margioris, and A. Gravanis
23 Molecular modeling of the interactions of a purine transporter with different substrate analogues: a first step towards the systematic development of antifungal drugs
George Diallinas
24 The effect of telmisartan and lekarnidipine on blood pressure and insulin resistance in hypertensive patients
P. Sarafidis, A. Lasaridis, L. Hatzistavri, P. Zebekakis and I. Tziolas
25 Infliximab (remicade) in the treatment of psoriatic arthritis and psoriasis: results of a one year open clinical study
L. Settas, T. Sfetsios, A. Theodoridou, E. Triantafyllidou and C. Mamali
26 The use of amifostine during continuous intraoperative intraperitoneal hyperthermic chemoperfusion (CIIPHCP) for peritoneal carcinomatosis from ovarian cancer
K. Chatzigeorgiou, S. Economou, N. Lyratzopoulos, G. Minopoulos, K. Manolas and N. Chatzigeorgiou
27 Evaluation of GnRH antagonists in ovarian stimulation protocols for IVF Cycles compared to GnRH agonists
F. Pournaropoulos, B.C. Tarlatzis, G. Grimbizis, M. Zafrakas, H. Bili, L. Zepiridis, G. Pados, J. Papadimas and J. Bontis
28 Corticotropin-releasing factor (CRF) receptors in the gastrointestinal system: physiological and pharmacological implications
Ekaterini Chatzaki, Yvette Taché and Dimitri E. Grigoriadis
29 Stress and drug pharmacokinetics
Christine Tesseromatis
30 Some conceptual and methodological issues interfering with the study of placebo effect
T. Spiropoulos, P. Andriopoulos and G. Papadopoulos
31 Laboratory and clinical medicine: a gap beyond reduction?
P. Andriopoulos, T. Spiropoulos and G. Papadopoulos
32 Effects of dopexamine on lipid peroxidation during aortic surgery in pigs: comparison with dopamine
Ioanna Andreadou, Georgia Kostopanagiotou, Antonis Doufas, Ioanna Chondroudaki, Thomas Kotsis, Eleftherios Kastellanos, Demetrios Rizos, Vassilios Smyrniotis
33 Chronic treatment with oleuroperin protects from the oxidative damage the reperfused myocardium and reduces the myocardial infarct size in rabbitsIoanna Andreadou, Efstathios K. Iliodromitis, Apostolos Agalias, Elias Bofilis, Anastasia Zoga, Maria Constantinou, P,Magiatis, Emmanuel Mikros, Alexios Leandros Skaltsounis, Dimitrios. Th. Kremastinos
34 Long term efficacy, tolerance and safety of liposo mal amphotericin B in children with CNS aspergil losis and acute lymphoblastic leukemia
F. Athanasiadou, A. Tragiannidis, Th. Papageorgiou and M. Stamou
35 Pharmacokinetic study of paclitaxel and carboplatin combination in patients with advanced cancer
A. Athanassiadis, E. Koumentaki, A. Tsona, S. Metallidis, P. Kollaras and P. Nikolaidis
36 The effect of serum vitamin B12 levels on the progression of Alzheimer’s disease dementia
E. Avdelidi, A. Touliou, K. Petsanis, A. Gouliova, M. Tsolaki and A. Kazis
37 In vitro susceptibility of oral candida species to antifungal agents in renal transplant recipients
M. Belazi, A. Velegraki, Th. Koussidou-Eremondi, D. Andreadis, F. Solonaki, S. Hini and D. Antoniades
38 Hemiplegia as a complication of treatment of childhood immune thrombocytopenic purpura with intravenously administered immunoglobulin
Vasiliki Demertzidou, loannis Xinias, Filareti Nalmpanti, Panagiotis Kardaras, Nikolaos Tsiouris, Kleomenis Spiroglou and loannis Tsiouris
39 Characteristic of decision making process during prescribing
Natasa Bordevic and Slobodan Jankovic
40 Hyphal damage activity of human monocytes primed with amphotericin B formulations against Aspergillus Fumigatus
J. Dotis, M, Simitsopoulou, A. Maloukou, M. Dalakiouridou and E. Roilides
41 Effect of trimetazidine on the fine stucture of ischaemic rat fast and slow muscles
L. Economou, A. Sioga, T. Loizidis and M. Albani
42 Ultrastructural alterations following 4-NQO administration, in rats, after experimental oral cavity cancer
L. Economou, A. Sioga, K. Antoniades, H. Tsoukali and A. Manthos
43 Immunohistochemical investigation of heat shock proteins in mice teratomata after in vivo administration of sodium valproate
E.N. Emmanouil-Nikoloussi, M.E. Manthou, A. Papadopoulou, E. Nikoloussis, Th. Papamitsou, A. Manthos and J. Thliveris
44 Hydroxyurea and thalidomide as regulators of caspase-3 activity on rat spleen and intestinal epithelia
H. Frangou-Massourides and A. Kotsis
45 Interaction between hsp90 and soluble guanylate cyclase: physiological significance and mapping of the domains mediating binding
C. Gerasimou, Z. Zhou, C. Roussos and A. Papapetropoulos
46 Blood transfusion-induced impairment of colonic anastomotic healing in rats is associated with de-creased TGFβ1 expression
A. Goulas, S. Apostolidis, L. Fidani, A. Michalopoulos, V. Papadopoulos, V, Mirtsou
47 Alterations in brain neurotransmitters in B(a)P exposed rats: role of D2 receptors
Panagiotis Harkitis, Panagiotis Tzimas, Marios Marselos, Elizabeth O, Johnson and Maria Konstandi
48 Effect of harp on the growth of human prostate cancer cells
M. Hatziapostolou and E. Papadimitriou1
49 Efficacy and safety of the imidapril (IM) in elderly patients with high cardiovascular risk
A. Hatzitolios, Ch. Savopoulos, M. Apostolopoulou, M. Kosmidou, Ch. Dimitroula, M. Baltatzi, G. Giannakoulas, G. Zioutas and G. Ziakas
50 Determination of histamine released from rat hypothalamic mast cells activated by compound 48/80
S. Kakavas and E. Tiligada
51 Toxicological aspects of fatal accidents in south-western Greece: a three-year experience (2001- 2003)
N.A. Karampelas, S.G Tziafeta, E. Papadimitriou and F. Skeparni
52 α2-adrenergic receptors activate mapk via PI-3k activation and EGF receptor transactivation in PC12 cells
Georgios Karkoulias, Orthodoxia Mastrogianni, Christodoulos Flordellis and Anastasios Lymperopoulos
53 The use or abuse sublingual nitrate tablets in clinical practice
G. Kazinakis, G. Giannoglou, K. Dimitrakopoulos, E. Dalamanga, A. Osama and G. Louridas
54 Novel anti-inflammatory molecules with reduced gastrointestinal toxicity perspectives for further applications
P.N. Kourounakis D. Galanakis, A.P. Kourounakis, K.C. Tsiakitzis, C. Doulgeris, E.A. Rekka, A.M. Gavalas and C. Kravaritou
55 Ketamine reverses the fentanyl-induced increase in NMDA-mediated synaptic transmission in CA1 area of the rat hippocampus
E. Kouvaras, E. Asouchidou, D. Michaloudis, N. Sakellaridis and E. Asprodini
56 A prodrug approach for the transportation of phytic acid derivatives inside cells
J.-M. Lehn, Y.C. Nicoiaou, K.C. Fylaktakidou and R. Greferath
57 Treatment of benign prostatic hyperplasia (BPH) by providing a long-term therapy with finasteride and a1ad blockers (tamsulosin)
D.A. Tsakiris, K. Wolf and M. Battegay
58 Effect of somatostatin analogs on chemically induced ischemia in rat retina
Niki Mastrodimou and Kyriaki Thermos
59 CRH-R1α structural domains critical for Gs-protein activation: evidence for distinct receptor active conformations associated with CRH and urocortin binding
Vassilis Mavros, Jing Chen Sofia Lazarou, George Liapakis and Dimitris K. Grammatopoulos
60 A synthetic peptide that corresponds to the C-terminal region of HARP inhibits angiogenesis in vivo and in vitro
K. Mikelis, A. Polykratis, A. Zompra, P. Cordopatis, P. Katsoris, J. Courty and E. Papadimitriou
61 Cetrorelix in ICSI cycles of women with one ovary
Nikolettos, B. Asimakopoulos, M. Simopoulou, A. Efthimiadou, S. Tsoulou, S. Al-Hasani and K. Diedrich
62 Somatostatin – nitric oxide interactions in the mouse retina
N.A. Papadioti, N. Mastrodimou, M.J. Low, K. Thermosh
63 Museum of pharmacology: foundation, aims, support and perspectives
J.S. Papadopulos, P. Galanopoulou, H. Carageorgiou, C. Liapi and A. Zarros
64 Blood lymphocyte blastogenesis in patients with haematological and endocrine disorders: a preliminary in vitro study
G. Papaioannou, F. Michelis, E. Tiligada and A. Delitheos
65 The effect of cyclosporin a on the secretion of matrix metalloproteases by vascular smooth muscle cells is mediated by reactive oxygen species
E. Papakonstantinou, U.T. Ruegg, A. Aletras, C. Pesintzaki, P. Lhote and G. Karakiulakis
66 Corticosteroids and ß2-adrenergic agonists differentially modulate the synthesis and Secretion of glycosaminoglycans by human lung cells
E. Papakonstantinou, M. Roth, M. Tamm and G. Karakiulakis
67 Genetic polymorphism of canine cytochrome P450 2D25 gene
I.S. Pappas and D.S. Katsiabas
68 Effects of an energy drink on central biogenic amines of wistar rat brain
P. Pappas, F. Yfanti, P. N. Karamanakos, M. Nikolaidou and M. Marselos
69 Irradiation of C6 glioma cells with X rays increases the expression of angiogenic genes and their angiogenic potential in vitro and in vivo
A. Parthymou, D. Kardamakis and E. Papadimitrou
70 Upregulation of renal water channels and sodium transporters in response to ovariectomy in rats
C. Sardeli, T.-H. Kwon, C. Li, M.A. Knepper, S. Nielsen and J. Frakiaer
71 Changes in the micturition profile and bladder AQP3 after ovariectomy in rats
C. Sardeli, D. Kouvelas, G. Karakiulakis, D. Hatichristou and V. Mirtsou-Fidani
72 The safety and activity of temozolomide (TMZ) in children with recurrent malignancies
V. Sidi, D.E. Koliouskas, E. Papakonstantinou and A. Karakoli
73 Amifostine efficacy and safety in paediatric patients with recurrence solid tumours
V. Sidi, G. Arsos, P. Triantafyllou, E. Papakonstantinou, A. Karakoli, N. Gompakis, I. Fragandrea and D.E. Koliouskas
74 HMG-CoA reductase inhibitors, but not calcium antagonists or angiotensin converting enzyme inhibitors, decrease the uptake of acetylated-LDL by human monocytes
A. Tavridou and V.G. Manolopoulos
75 Somatostatin receptors in the ventral pallidum modulate rat locomotor activity
K. Thermos, A. Kastellakis, D. Papasava, K. Antoniou, S. Kyrkouli and A. Marazioti
76 Tie2 agonists downreguiate angiopoietin-2 production
S. Tsigkos, Z. Zhou, C. Roussos and A. Papapetropoulos
77 The anxiolytic profile and the withdrawal effects of chlordiazepoxide evaluated in the BKW and C57BL/6J mice
Carolina Stavroula, Tsitsirigou and Alison Bratt
78 Use of alternative specimens in TDM
H. Tsoukali and N. Raikos
79 Toxicological aspects of sudden and violent deaths in southwestern Greece: a three-year review (2001-2003)
S.G. Tziafeta, N.A. Karampelas, E. Papadimitriou and F. Skeparni
80 Implication of phosphorylation/dephosphorylation in the adaptive heat shock response
I. Vovou, K. Papamichael, A. Delitheos and E. Tiligada
81 Childhood dyspepsia: ranitidine or cispapride
loannis Xinias, Vasilrki Demertzidou, Georgios Paroutoglou, Nikoiaos Nikolaidis, Olga Giouleme, loannis Tsiouris, Panagiotis Kardaras and Kleomenis Spiroglou

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ΤOΜΟΣ 18 (2004) – ΤΕΥΧΟΣ 1 – Review of Clinical Pharmacology and Pharmacokinetics-Διεθνής Έκδοση
VOLUME 18 (2004) – ISSUE 1 – Review of Clinical Pharmacology and Pharmacokinetics-International Edition
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