Τίτλος – Title
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Μηχανική Υποστήριξη Ασθενών με Διατατική Μυοκαρδιοπάθεια Mechanical Support of Patients with Dilated Cardiomyopathy |
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Συγγραφέας – Author
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Κυριάκος Αναστασιάδης1, Χρήστος Παπακωνσταντίνου2 1Καρδιοχειρουργός, Επίκουρος Καθηγητής, Ιατρική Σχολή, Αριστοτέλειο Πανεπιστήμιο, Α’ Κλινική Θώρακος, Καρδιάς και Μεγάλων Αγγείων, Π.Γ.Ν. ΑΧΕΠΑ, Θεσσαλονίκη, Ελλάς Kyriakos Anastasiadis1, Christos Papaconstantinou2 1Assistant Professor, Dept. of Cardiothoracic Surgery, Medical School, Aristotle University, AHEPA University Hospital, Thessaloniki, Hellas |
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Παραπομπή – Citation
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Αναστασιάδης,Κ., Παπακωνσταντίνου,Χ. : Μηχανική Υποστήριξη Ασθενών με Διατατική Μυοκαρδιοπάθεια, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 28: 187-192 (2010) Anastasiadis,K., Papaconstantinou,Ch. : Mechanical Support of Patients with Dilated Cardiomyopathy, Epitheorese Klin. Farmakol. Farmakokinet. 28: 187-192 (2010) |
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Ημερομηνία Δημοσιευσης – Publication Date
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1 Δεκεμβρίου 2010 – 2010-12-01
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Γλώσσα Πλήρους Κειμένου –
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Ελληνικά – Greek |
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Λέξεις κλειδιά – Keywords
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Λοιποί Όροι – Other Terms
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Στατιστική Μελέτη Statistical Study |
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Περίληψη – Summary
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– Dilated cardiomyopathy (DCM) affects mainly the muscle of the left ventricle of the heart, which dilates, weakens and hence leads to heart failure. Despite the prognostic and symptomatic benefit that conservative therapy with modern drugs has offered lately, heart transplantation still remains the gold standard treatment to the end-stages of the disease. However, donor shortage has led research to improve interventional cardiology techniques, such as cardiac resynchronization therapy, and cardiac surgical procedures, such as left ventricular assist devices (LVADs) and total artificial heart. Lately, LVADs are used not only as bridge to heart transplantation, but also as bridge to recovery or for long term (permanent) support. The effort to improve the outcome and decrease the complications from these devices has led to the development of three generations of LVADs. Further application of this technology to the treatment of diseases who lead in heart failure, such as DCM, may lead researchers to invent even better devices in the future. |
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Αναφορές – References
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1. Kopecky S.L., Gersh B.J.: Dilated cardiomyopathy and myocarditis: natural history, etiology, clinical manifestations, and management. Curr. Probl. Cardiol. 12: 569-647 (1987)
2. Hunt S.A., Abraham W.T., Chin M.H., Feldman A.M., Francis G.S., Ganiats T.G., et al.: 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the diagnosis and management of heart failure in adults: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 119: e391-e479 (2009) 3. Sukhija R., Mehta V., Leonardi M., Mehta J.L.: Implantable cardioverter defibrillators for prevention of sudden cardiac death. Clin. Cardiol. 30: 3-8 (2007) 4. Rivera D.A., Bristow M.R.: Cardiac resynchronization – a heart failure perspective. Ann. Noninvasive Electrocardiol. 10(Suppl): S16-S23 (2005) 5. Jessup M., Brozena S.: Heart failure. N. Engl. J. Med. 348: 2007-2018 (2003) 6. Smolens I.A., Pagani F.D., Bolling S.: Mitral valve repair in heart failure. Eur. J. Heart Fail. 2: 365-371 (2000) 7. Louis L.B., Sun B.: Advances in mechanical circulatory support. Curr. Opin. Organ. Transplant. 13: 522-525 (2008) 8. Matsuda H., Matsumiya G.: Current status of left ventricular assist devices: the role in bridge to heart transplantation and future perspectives. J. Artif. Organs 6: 157-161 (2003) 9. Windecker S.: Percutaneous left ventricular assist devices for treatment of patients with cardiogenic shock. Curr. Opin. Crit. Care 13: 521-527 (2007) 10. Trost J.C., Hillis L.D.: Intraaortic balloon counterpulsation. Am. J. Cardiol. 97: 1391-1398 (2006) 11. Siegenthaler M.P., Brehm K., Strecker T., Hanke T., Nötzold A., Olschewski M., et al.: The Impella Recover microaxial left ventricular assist device reduces mortality for postcardiotomy failure: a three center experience. J. Thorac. Cardiovasc. Surg. 127: 812-822 (2004) 12. Reverdin S., Gregoric I.D., Kar B., Loyalka P., Bieniarz M.C., LeMaire S.A., et al.: Bridge to transplantation with the TandemHeart: bending the indications in a chronic aortic dissection patient with postcardiotomy shock. Tex. Heart Inst. J. 35: 340-341 (2008) 13. John R., Liao K., Lietz K., Kamdar F., Colvin-Adams M., Boyle A., et al.: Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure. J. Thorac. Cardiovasc. Surg. 134: 351-358 (2007) 14. Marasco S.F., Lukas G., McDonald M., McMillan J., Ihle B.: Review of ECMO (extra corporeal membrane oxygenation) support in critically ill adult patients. Heart Lung Circ. 17(Suppl): S41-S4714 (2008) 15. Anastasiadis K.: Mechanical support of the circulatory system. Hellenic J. Cardiol. 44: 341-347 (2003) 16. Deng M., Edwards L., Hertz M., Rowe A., Keck B., Kormos R., et al.: Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: third annual report – 2005. J. Heart Lung Transplan. 24: 1182-1187 (2005) 17. Holman W., Pae W., Teutenberg J., Acker M., Naftel D., Sun B., et al.: INTERMACS: interval analysis of registry data. J. Am. Coll. Surg. 208: 755-761 (2009) 18. El-Banayosy A., Körfer R., Arusoglu L., Kizner L., Morshuis M., Milting H., et al.: Device and patient management in a bridge-to-transplant setting. Ann. Thorac. Surg. 71(Suppl): S98-S102 (2001) 19. Deng M.C., Edwards L.B., Hertz M.I., Rowe A.W., Keck B.M., Kormos R., et al.: Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: second annual report – 2004. J. Heart Lung Transplant. 23: 1027-1034 (2004) 20. Rose E.A., Gelijns A.C., Moskowitz A.J., Heitjan D.F., Stevenson L.W., Dembitsky W., et al.: Long-term mechanical left ventricular assistance for end-stage heart failure. N. Engl. J. Med. 345: 1435-1443 (2001) 21. Lietz K., Miller L.W.: Destination therapy: current results and future promise. Semin. Thorac. Cardiovasc. Surg. 20: 225-233 (2008) 22. Hetzer R., Müller J.H., Weng Y., Meyer R., Dandel M.: Bridging-to-recovery. Ann. Thorac. Surg. 71(Suppl): S109-S113 (2001) 23.Yacoub M.H.: A novel strategy to maximize the efficacy of left ventricular assist devices as a bridge to recovery. Eur. Heart J. 22: 534-540 (2001) 24. Birks E.J., Tansley P.D., Hardy J., George R.S., Bowles C.T., Burke M., et al.: Left ventricular assist device and drug therapy for the reversal of heart failure. N. Engl. J. Med. 355: 1873-1884 (2006) 25. Copeland J.G., Arabia F.A., Tsau P.H., Nolan P.E., McClellan D., Smith R.G., et al.: Total artificial hearts: bridge to transplantation. Cardiol. Clin. 21: 101-113 (2003) 26. Clegg A.J., Scott D.A., Loveman E, Colquitt J., Hutchinson J., Royle P., et al.: The clinical and cost-effectiveness of left ventricular assist devices for end-stage heart failure: a systematic review and economic evaluation. Health Technol. Assess. 9: 1-132 (2005) 27. Dowling R.D., Gray L.A., Etoch S.W., Laks H., Marelli D., Samuels L., et al.: Initial experience with the AbioCor implantable replacement heart system. J. Thorac. Cardiovasc. Surg. 127: 131-141 (2004) 28. Westaby S., Jarvik R., Freeland A., Pigott D., Robson D., Saito S., et al.: Postauricular percutaneous power delivery for permanent mechanical circulatory support. J. Thorac. Cardiovasc. Surg. 123: 977-983 (2002)
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