Τίτλος – Title | Ιική Καρκινογένεση
Viral Carcinogenesis |
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Συγγραφέας – Author | Σταύρος Κοτταρίδης
Κέντρο Ογκολογικής Ερεύνης και Πειραματικής Χειρουργικής «Γ. ΠΑΠΑΝΙΚΟΛΑΟΥ» Stavros D. Kottaridis Papanikolaou Research Center of Oncology |
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Παραπομπή – Citation | Κοτταρίδης, Σ.: Ιική Καρκινογένεση, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 3: 178-194 (1983)
Kottaridis, S.D.: Viral Carcinogenesis, Epitheorese Klin. Farmakol. Farmakokinet. 3: 178-194 (1983) |
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Ημερομηνία Δημοσιευσης – Publication Date | Οκτώβριος 1983 – October 1983 | |
Γλώσσα Πλήρους Κειμένου – Full Text Language |
Ελληνικά – Greek | |
Παραγγελία – Αγορά – Order – Buy |
Ηλεκτρονική Μορφή: pdf (15 €) – Digital Type: pdf (15 €) pharmakonpress[at]pharmakonpress[.]gr |
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Λέξεις κλειδιά – Keywords | Ογκογόνοι ιοί, ογκογονίδια, καρκινογένεση, DNA
Oncogenic viruses, oncogenes, carcinogenesis, DNA |
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Λοιποί Όροι – Other Terms | Άρθρο Article |
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Περίληψη – Summary | In the last 30 years tumor virologists have been involved in the study of molecular biology of cancer. Four groups of oncogenic viruses, the papova-, retro-, adeno- and herpes viruses have been associated with animal and human tumors and have provided powerful experimental systems for the study of oncogenesis. Many of these viruses have transforming genes “oncogenes” and the products of these genes have been well studied. Integration of viral genome into the host chromosome enable the genome of tumor viruses to survive within the cell as a separate unit and to reproduce independently. Integration can enhance the expression of adjacent cellular-genes. If the activated gene is a cellular oncogene, tumorigenesis may be initiated. The recognition and isolation of cellular oncogenes has set forth new concepts on the mechanisms of carcinogenesis. | |
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