Τόμος 1 (1983) – Τεύχος 3 – Άρθρο 5 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 1 (1983) – Issue 3 – Article 5 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Τίτλος – Title Τα Κυτταροστατικά φάρμακα και η Θέση τους στη Θεραπευτική των κακοήθων Νεοπλασιών

Cytotoxic Drugs and their Place in the Treatment of Malignant Neoplasias

Συγγραφέας – Author Γεώργιος Π. Σταθόπουλος

George P. Stathopoulos

Παραπομπή – Citation Σταθόπουλος, Γ.Π.: Τα Κυτταροστατικά φάρμακα και η Θέση τους στη Θεραπευτική των κακοήθων Νεοπλασιών, Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 3: 219-230 (1983)

Stathopoulos, G.P.: Cytotoxic Drugs and their Place in the Treatment of Malignant Neoplasias, Epitheorese Klin. Farmakol. Farmakokinet. 3: 219-230 (1983)

Ημερομηνία Δημοσιευσης – Publication Date Οκτώβριος 1983 – October 1983
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Ελληνικά – Greek
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Λέξεις κλειδιά – Keywords Χημειοθεραπεία, κυτταροστατικά φάρμακα, φαρμακοκινητική

Cytotoxic chemotherapy, cytotoxic drugs, pharmakokinetics

 
Λοιποί Όροι – Other Terms Άρθρο
Article
 
Περίληψη – Summary In this review article the introduction and development of cytotoxic chemotherapy in malignant tumours are initially described. On the basis of certain experimental works done during the last twenty years in particular, the action of cytotoxic drugs on the cell kinetics of normal and malignant cells is analyzed and the possible selectivity mechanism of those drugs on the malignant cell population is discussed. Included furthermore is a list of circulating drugs grouped in classes, their pharmacokinetics and what is known about their mechanism of action.  
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