Τόμος 14 (1996) – Τεύχος 3 – Άρθρο 5 – Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση – Volume 14 (1996) – Issue 3 – Article 5 – Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

 

Τίτλος – Title

Φάρμα­κα και Μα­στός

Drugs and the Breast

Συγγραφέας – Author

Βα­σί­λης Κόκ­κας

Ερ­γα­στή­ριο Φαρ­μα­κο­λο­γί­ας, Ια­τρι­κό Τμή­μα, Α­ρι­στοτέ­λειο Πα­νε­πι­στή­μιο Θεσ­σα­λο­νί­κης, Θεσσαλονίκη, Ελ­λάς

Basilis Kokkas

Department of Pharmacology, Medical Faculty, Aristotle University of Thessaloniki, Greece

Παραπομπή – Citation

Κόκκας,Β. : Φάρμα­κα και Μα­στός , Επιθεώρηση Κλιν. Φαρμακολ. Φαρμακοκινητ. 14 :  161-167 (1996)

Kokkas,B. : Drugs and the Breast, Epitheorese Klin. Farmakol. Farmakokinet. 14 :  161-167 (1996)

Ημερομηνία Δημοσιευσης – Publication Date
15-09-1996
Γλώσσα Πλήρους Κειμένου –
Full Text Language

Ελληνικά – Greek

Παραγγελία – Αγορά –
Order – Buy
Ηλεκτρονική Μορφή: pdf (15 €)
Digital Type: pdf (15 )
pharmakonpress[at]pharmakonpress[.]gr
Λέξεις κλειδιά – Keywords

Προλακτίνη, δοπαμίνη, γαλουχία, γαλακτόρροια, γυναικο­μαστία

Prolactin, dopamine, lactation, galactor­rhea, gynecomastia
Λοιποί Όροι – Other Terms

Άρθρο

Article

Περίληψη – Summary

Στην α­να­σκό­πη­ση αυ­τή γί­νε­ται προσπά­θεια που στη­ρί­ζε­ται στη διε­θνή βι­βλιο­γρα­φί­α και α­πο­σκο­πεί να δώ­σει πλη­ρο­φο­ρί­ες σφαι­ρι­κά για τις ε­πι­δρά­σεις των φαρ­μά­κων στη λει­τουρ­γί­α του μα­στού κα­θώς και στους πι­θα­νούς κιν­δύ­νους τό­σο για το μα­στό ό­σο και για το θη­λά­ζον βρέ­φος. Α­να­πτύσ­σο­νται τα φάρ­μα­κα που δρούν θε­τι­κά ή αρ­νη­τι­κά στη γα­λου­χί­α, κα­θώς και τα φάρ­μα­κα που μπο­ρεί να προ­κα­λέ­σουν γα­λακτόρ­ροια στις γυ­ναί­κες και γυ­ναι­κο­μα­στί­α στους άν­δρες. Γί­νε­ται ε­πί­σης ανα­φο­ρά στα φάρ­μα­κα που εί­ναι ύ­πο­πτα για την πρό­κλη­ση καρ­κίνου του μαστού και η α­να­σκό­πη­ση τε­λειώ­νει με σύ­ντο­μη α­να­φο­ρά στους κιν­δύ­νους που συνε­πά­γε­ται για το βρέ­φος η χρή­ση ο­ρι­σμέ­νων φαρ­μά­κων κα­τά τη διάρ­κεια του θη­λα­σμού.

This review based on international references tries to give informations con­cerning the influence of pharmaceutical substances on breast function. The ac­tion of drugs that influence lactation as well as drugs that provoke galactor­rhea to the women and gynecomastia to the men is also described. Substances that are suspected to provoke breast cancer are also referred. Finally this ar­ticle presents the drugs that are excreted in the breast milk and suggests which of them must be avoided  during lactation.

Αναφορές – References1.
  1. Granner D.: Pituitary and Hypothalamic Hormones. Ιn: Harper’s Biochemistry (Murray R., Granner D. et al., eds); p. 478, Prentice International Inc., Connecticut, 1990
  2. Findling J., Tyrrell B.: Anterior Pituitary Gland. In: Basic and Clinical En­docrinology (Greenspan F., ed.); p.79, Pren­tice International Inc., Connecticut, 1991
  3. Daniels G., Martin J.: Neuroendocrine regulation and dis­eases of the an­terior pituitary and hypothalamus. In: Harri­son’s Principles of Internal Medicine (Wilson J., Braunwald E., et al., eds); p.1655, McGraw-Hill Inc., New York, 1991
  4. Breckwoldt M., Zahradnik H., Neulen J.: Classification and diagnosis of ovarian insufficiency. In: Infertility – Male and Female (Insler V., Lunenfield B., eds); p.224, Churchill-Livingston, New York, 1993
  5. Wilson J.: Endocrine disorders of the breast. In: Harri­son’s Principles of In­ternal Medicine (Wilson J., Braunwald E., et al., eds); p.1795, McGraw-Hill Inc., New York, 1991
  6. Laurence D., Bennet P.: Clinical Pharmacology; Churchil-Livingstone, New York, 1987
  7. Melis G., Paoletti A., Mais V., Mastrapasqua N., Strigini F.: The effects of the GABAergic drug, sodium valproate on prolactin secretion in normal and prolacti­naemic subjects. J. Clin. Endocrinol. Metab. 54: 485-489 (1982)
  8. Graves C.: Agents that cause contraction or relaxation of the uterus. In: Good­man and Gilman, The Pharmacological Basis of Therapeutics (Hardman J., et al, eds) p. 939, McGraw Hill, New York (1996)
  9. Badawy S., Rebscher F., Kohn L., Walfe H., Oates R., Moses A.: The relation­ship between oral contraceptive use and subsequent development of hyperprolactinaemia. Fertil. Steril. 36: 464-467 (1981)
  10. Aono T., Shioji T., Kinugasa T., Onish T., Kurachi K.: Clinical and en­docrinological analysis of patients with galac­torrhoea and menstrual disorders due to sulpiride or meto­clopramide. J. Clin. Endocrinol. Metab. 47: 675-680 (1976)
  11. Cann P., Read N., Holdsworth C.: Galactorrhoea as side effect of domperidone. Br. Med. J. 286: 1395-1396 (1983)
  12. Brown W., Laughren T.: Tolerance to the prolactin ele­vating effects of neuroleptics. Phychiat. Res. 5: 317-322 (1981)
  13. Muller E., Locatelli V., Cella S., Penalva A., Noveli A., Cocchi D.: Prolactin lowering and releasing drugs. Mecha­nisms of action and therapeutic applications. Drugs 25: 399-432 (1983)
  14. Krawiec J., Krugliak P., Levy J., Lamorecht S., Odes M.: Effect of oral cimetidine on plasma prolactin. Isr. J. Med. Sci. 17: 1183-1184 (1981)
  15. Mendelson J., Ellingboe J., Mello N., Kuehnle J.: Buprenorphine effects on plasma luteinizing hormone and prolactin in male heroin addicts. J. Pharmacol. Exp. Ther. 220: 252-255 (1982)
  16. Ehni G., Eckles N.: Interruption of pituitary stalk in pa­tients with mam­mary cancer. J. Neurosurg. 16: 628-652 (1959)
  17. Durant P., Borrone C., Scarabichi S., Razzi A.: Hyper­pigmantation of breast areolae and external genitals with gy­naecomastia following griseofulvin treatment. Minerva Med. 55: 2422-2425 (1964)
  18. Gerniez-Rieux C., Tacquet A., Macquet V.: Perfusions with ethionamide in the treatment of pulmonary tuberculosis. G. Ital. Chemioter. 10: 87-98 (1963)
  19. Conn H.: Digitalis therapy and gynecomastia. J.A.M.A. 190: 1018-1019 (1964)
  20. Rose L., Underwood R., Newmark S., Kischi E., Wil­liams G.: Pathophysiology of spirolactone induced gyneco­mastia. Ann. Intern. Med. 87: 398-403 (1977)
  21. Miyatake A., Noma K., Nakao R., Morimoto Y., Yamamura Y.: Increased serum oestrone and oestradiol following spirolactone administration in hypertensive men. Clin. Endocr. 9: 523-533 (1978)
  22. Moerch H., Magelund G.: Gynaecomastia and diazepam abuse. Lancet 1: 1344-­1345 (1979)
  23. Steiner J., Cassar J., Mashiter K., Dawes I., Russell-Fraser T.: Effects of methyldopa on prolactin and growth hormone. Br. Med. J. 1: 1186-1188 (1976)
  24. Olusi S.: Hyperprolactinaemia in patients with suspected cannabis induced gynecomastia. Br. Med. J. 280: 255-258 (1980)
  25. Check J., Murdock M., Caro J., Hermel M.: Cystic gy­necomastia in a male treated with clomiphene citrate. Fertil-Steril 30: 713-715 (1978)
  26. Friedman N., Plymate S.: Initial screening for carcino­genicity of commonly used drugs. J. Nat. Cancer Inst. 65: 723-733 (1980)
  27. Bezuidenhont D.: Gynecomastia tydeus simetidin-tera­pie. S. Afr. Med. J. 54: 263­267 (1978)
  28. Sharpe P., Hawkins B.: Efficacy and safety of cimetid­ine. Long-term treat­ment with cimetidine. In: Proc. 2nd Int. Symp. Histamine H2receptor antagonists (Burland W., Simpkins M., eds); pp. 358-366, Excerpta Medica, Amster­dam, 1977
  29. Williams R.: Breast and thyroid cancer and malignant melanoma promoted by alcohol-induced pituitary secretion of prolactin, TSH and MSH. Lancet 2: 996-999 (1976)
  30. Rosenberg L., Slone D., Shapiro S., Kaufman D., Helm­rich S.: Breast cancer and alcoholic beverage consumption. Lancet 1: 267-271 (1982)
  31. LaVecchia C., Franceschi S., Cuzick J.: Alcohol and breast cancer. Lancet 1: 621-624 (1982)
  32. Laska E., Seigel C., Meisner M., Fischer S., Wanderling J.: Matched-pairs study of reserpine use and breast cancer. Lancet 2: 296-300 (1975)
  33. Asmstrong B., Skegg D., White G., Doll R.: Rauwolfia derivatives and breast cancer in hypertensive women. Lan­cet 2: 8-12 (1976)
  34. Armstrong B., Skegg D., White G., Doll R.: Rawolfia derivatives and breast cancer in women. Lancet 2: 672-675 (1974)
  35. Horrobin D., Chayur T., Karmali R.: Mind and cancer. Lancet 1: 675-677 (1974)
  36. Boyland E.: Diazepam and tumour promotion. Lancet 1: 455-458 (1981)
  37. Kaufman D., Shapiro S., Slone D., Rosenberg L., Helm­rich S., Miettinen O., Stolley P., Levey M.: The risk of breast cancer. Lancet 1: 537-539 (1982)
  38. Gambrell D., Massey F., Castenada T., Boddie A.: Es­trogen therapy and breast cancer in postmenopausal women. J. Am. Geriat. Soc. 28: 251-257 (1986)
  39. Stanford J., Weiss N., Voigt F.: Combined estrogen and prolactin hormone replacement therapy in relation to risk of breast cancer in middle aged women. J.A.M.A. 274: 137-142 (1995)
  40. Πινακίδης Μ., Μπούτης Λ.: Καρκίνος μαστού; Univer­sity Studio Press, Θεσσαλονίκη, 1993
  41. Hemminki E.: Oral contraceptives and breast cancer. Br. Med. J. 313: 63-64 (1996)
  42. Παραδέλλης Α.: Κλινική Φαρμακολογία – Ειδικά θέματα. Κύκλος πρώτος. University Studio, Θεσσαλονίκη, 1990
  43. Benet L., Kroetz D., Sheiner L.: Pharmacokinetics. In: Goodman and Gilman’s: The Pharmacological Basis of Therapeutics (Hardmann J, et al., eds); p.3, McGraw-Hill, New York, 1990
  44. Abramowiez M.: Drugs in breast milk. Med. Letter 21: 21-24 (1979)
  45. Anderson P.: Drugs and breast feeding. Drug Intell. Clin. Pharmacol. 11: 208-223 (1977)
  46. Briggs G., Breeman R., Yaffe S.: Drugs in pregnancy and lactation (Brown C., ed.); Williams and Wilkings, Balti­more, 1986
  47. Chaplin S., Sanders G., Smith J.: Drug excretion in hu­man breast milk. Adv. Drug React. Acute Pois. Rev. 1: 255-287 (1982)
  48. Platzker A., Lew C., Stewart D.: Drug administration via breast milk. Hosp. Pract. 15: 111-122 (1980)

Online ISSN 1011-6575

Άρθρα Δημοσιευμένα σε αυτό το Περιοδικό Καταχωρούνται στα:
Chemical Abstracts

Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE
SCImago Journal and Country Rank Factor

Articles published in this Journal are Indexed or Abstracted in:
• Chemical Abstracts
• Elsevier’s Bibliographic Databases: Scopus, EMBASE, EMBiology, Elsevier BIOBASE
SCImago Journal and Country Rank Factor

Άρθρα Δημοσιευμένα στην Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής-Ελληνική Έκδοση
Articles Published in Epitheorese Klinikes Farmakologias και Farmakokinetikes-Greek Edition

Συντακτικη Επιτροπή-Editorial Board

ΕΤΗΣΙΑ ΣΥΝΔΡΟΜΗ – ANNUAL SUBSCRIPTION
Γλώσσα Πλήρους Κειμένου –
Full Text Language
Ελληνικά – Greek
Παραγγελία – Αγορά –
Order – Buy
Ηλεκτρονική Μορφή: pdf (70 €) –
Digital Type: pdf (70 €)
pharmakonpress[at]pharmakonpress[.]gr
Έντυπη Μορφή (70 € + έξοδα αποστολής)
Printed Type (70 € + shipping)
pharmakonpress[at]pharmakonpress[.]gr

 

Προσθέστε στους σελιδοδείκτες το μόνιμο σύνδεσμο.

Τα σχόλια είναι απενεργοποιημένα.